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Robert O Ryan Selected Research

Apolipoproteins A

3/2016Apolipoprotein A-V gene therapy for disease prevention / treatment: a critical analysis.
12/2015Apolipoprotein A-V is present in bile and its secretion increases with lipid absorption in Sprague-Dawley rats.
4/2015Apolipoprotein A-V deficiency enhances chylomicron production in lymph fistula mice.
4/2013Influence of apolipoprotein A-V on the metabolic fate of triacylglycerol.
3/2013Gene transfer of apolipoprotein A-V improves the hypertriglyceridemic phenotype of apoa5 (-/-) mice.
5/2012Apolipoprotein A-V dependent modulation of plasma triacylglycerol: a puzzlement.
12/2010Intravenous injection of apolipoprotein A-V reconstituted high-density lipoprotein decreases hypertriglyceridemia in apoav-/- mice and requires glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1.
5/2010Apolipoprotein A-V associates with intrahepatic lipid droplets and influences triglyceride accumulation.
11/2009Apolipoprotein A-V N-terminal domain lipid interaction properties in vitro explain the hypertriglyceridemic phenotype associated with natural truncation mutants.
4/2009The ins (cell) and outs (plasma) of apolipoprotein A-V.
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Robert O Ryan Research Topics

Disease

6Hypertriglyceridemia
03/2016 - 11/2009
5Inborn Errors Metabolism (Inborn Errors of Metabolism)
04/2022 - 01/2016
5Hepatocellular Carcinoma (Hepatoma)
06/2014 - 02/2006
4Barth Syndrome
01/2018 - 08/2015
4Heart Diseases (Heart Disease)
03/2016 - 05/2012
3Mitochondrial Diseases (Mitochondrial Disease)
10/2022 - 08/2015
3Neoplasms (Cancer)
10/2022 - 08/2011
3Atherosclerosis
11/2021 - 04/2013
3Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
08/2011 - 07/2010
2Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
01/2017 - 08/2015
2Fistula
12/2015 - 04/2015
2Lymphoma (Lymphomas)
08/2015 - 08/2011
2Alzheimer Disease (Alzheimer's Disease)
10/2013 - 01/2011
1Dehydration (Water Stress)
01/2022
1Heart Failure
10/2021
1Muscular Diseases (Myopathy)
10/2021
1Cardiotoxicity
01/2020
1Neuroblastoma
10/2018
1Atherosclerotic Plaque (Atheroma)
06/2017
1Cardiomyopathies (Cardiomyopathy)
01/2017
1Lactic Acidosis
01/2017
1Cardiovascular Diseases (Cardiovascular Disease)
03/2016
1Ataxia (Dyssynergia)
08/2015
1Propionic Acidemia
08/2015
1Methylmalonic acidemia
08/2015
1Inborn Genetic Diseases (Disease, Hereditary)
08/2015
1Non-alcoholic Fatty Liver Disease
01/2015
1Glioma (Gliomas)
11/2014
1Glioblastoma (Glioblastoma Multiforme)
05/2014
1Amyloid Plaque
10/2013
1Mycoses (Diseases, Fungus)
01/2012
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2011
1Leishmaniasis
07/2009
1Infections
04/2006
1Candidiasis (Moniliasis)
02/2006

Drug/Important Bio-Agent (IBA)

11Apolipoproteins AIBA
03/2016 - 08/2008
4Cardiolipins (Cardiolipin)IBA
10/2022 - 08/2015
4LipidsIBA
01/2020 - 11/2009
4Phospholipids (Phosphatides)FDA LinkGeneric
01/2017 - 12/2010
4CurcuminIBA
11/2014 - 04/2011
3AcidsIBA
01/2022 - 01/2017
3Proteins (Proteins, Gene)FDA Link
11/2021 - 08/2008
3CholesterolIBA
06/2017 - 10/2012
3Apolipoprotein A-VIBA
04/2015 - 08/2008
3Apolipoproteins E (ApoE)IBA
05/2014 - 01/2011
3Biological ProductsIBA
05/2014 - 08/2011
3Triglycerides (Triacylglycerol)IBA
04/2013 - 05/2012
3Lipoproteins (Lipoprotein)IBA
01/2011 - 08/2008
23-methylglutaconic acidIBA
04/2022 - 01/2016
2Acetyl Coenzyme A (Acetyl-CoA)IBA
04/2022 - 01/2016
2Coenzyme A (CoA)IBA
01/2022 - 01/2016
2diazonaphthalenedisulfonic acid (NDS)IBA
05/2014 - 04/2011
2ApolipoproteinsIBA
10/2013 - 04/2011
2HDL LipoproteinsIBA
10/2012 - 12/2010
2Amphotericin B (Amphotericin)FDA LinkGeneric
01/2012 - 04/2006
1Doxorubicin (Adriamycin)FDA LinkGeneric
10/2022
1AnthracyclinesIBA
10/2022
13-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)IBA
01/2022
1UbiquinoneIBA
10/2021
1EnzymesIBA
03/2021
1Leucine (L-Leucine)FDA Link
03/2021
1coenzyme Q10 (CoQ10)IBA
01/2020
1DNA (Deoxyribonucleic Acid)IBA
01/2020
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2020
1Adenosine Triphosphate (ATP)IBA
01/2017
1Wnt ProteinsIBA
08/2016
1Cell Surface ReceptorsIBA
08/2016
1propionyl-coenzyme A (propionyl-CoA)IBA
08/2015
1Isoleucine (L-Isoleucine)FDA Link
08/2015
1Apolipoprotein A-I (Apolipoprotein A1)IBA
08/2015
1Immunoglobulin FragmentsIBA
08/2015
1TrioleinIBA
04/2015
1EmulsionsIBA
04/2015
1ChylomicronsIBA
04/2015
1DisulfidesIBA
10/2014
1Oxidoreductases (Dehydrogenase)IBA
06/2014
1Small Interfering RNA (siRNA)IBA
06/2014
1Glyceraldehyde 3-Phosphate (Glyceraldehyde 3 Phosphate)IBA
06/2014
1Peptides (Polypeptides)IBA
10/2013
1Amyloid (Amyloid Fibrils)IBA
10/2013
1Cyclin D1IBA
08/2011
1Apolipoprotein E4IBA
01/2011
1Protein Isoforms (Isoforms)IBA
01/2011
1high density lipoprotein binding proteinIBA
12/2010
1Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA
12/2010
1Tretinoin (Retinoic Acid)FDA LinkGeneric
07/2010
1Retinoic Acid Receptors (Retinoic Acid Receptor)IBA
07/2010
1Arginine (L-Arginine)FDA Link
07/2009
1ArginaseIBA
07/2009
1Protein Sorting Signals (Signal Peptide)IBA
08/2008
1Conditioned Culture MediaIBA
08/2008
1Oleic Acid (Oleate)IBA
08/2008
1Green Fluorescent ProteinsIBA
08/2008
1Dihydrotachysterol (AT 10)IBA
02/2006
1MicellesIBA
02/2006
1Deoxycholic Acid (Sodium Deoxycholate)IBA
02/2006
1Anti-Bacterial Agents (Antibiotics)IBA
02/2006

Therapy/Procedure

6Therapeutics
01/2020 - 07/2009
1Intravenous Injections
12/2010
1Drug Therapy (Chemotherapy)
07/2010